16 letter Words with the Lowest Letter Frequency Scores
            
            
            
                                
                    | # | Word | Frequency Score | Letters (Alpha) | Unique Letter Count | Ranking (Len) | 
|---|
                                        
                                                | 441 | salpingemphraxis | 8,676 | aeghilmnprsx | 12 | 1,146 | 
                                        
                                                | 442 | nucleohyaloplasm | 8,684 | acehlmnopsuy | 12 | 1,145 | 
                                        
                                                | 443 | hydrocarbostyril | 8,687 | abcdhilorsty | 12 | 1,144 | 
                                        
                                                | 444 | hyperorganically | 8,690 | aceghilnopry | 12 | 1,143 | 
                                        
                                                | 445 | parapsychologist | 8,698 | acghiloprsty | 12 | 1,142 | 
                                        
                                                | 446 | churchwardenship | 8,701 | acdehinprsuw | 12 | 1,141 | 
                                        
                                                | 447 | circumhorizontal | 8,707 | achilmnortuz | 12 | 1,140 | 
                                        
                                                | 448 | centrifugalizing | 8,709 | acefgilnrtuz | 12 | 1,139 | 
                                        
                                                | 449 | undersheriffwick | 8,714 | cdefhiknrsuw | 12 | 1,138 | 
                                        
                                                | 450 | physiognomonical | 8,714 | acghilmnopsy | 12 | 1,137 | 
                                        
                                                | 451 | splanchnopleuric | 8,715 | acehilnoprsu | 12 | 1,136 | 
                                        
                                                | 452 | balneophysiology | 8,716 | abeghilnopsy | 12 | 1,135 | 
                                        
                                                | 453 | hydropericardium | 8,719 | acdehimopruy | 12 | 1,134 | 
                                        
                                                | 454 | nondyspeptically | 8,726 | acdeilnopsty | 12 | 1,133 | 
                                        
                                                | 455 | pseudobiological | 8,729 | abcdegilopsu | 12 | 1,132 | 
                                        
                                                | 456 | cystoradiography | 8,735 | acdghioprsty | 12 | 1,131 | 
                                        
                                                | 457 | deoxyribonucleic | 8,736 | bcdeilnoruxy | 12 | 1,130 | 
                                        
                                                | 458 | nonconjecturably | 8,745 | abcejlnortuy | 12 | 1,129 | 
                                        
                                                | 459 | thigmotropically | 8,748 | acghilmoprty | 12 | 1,128 | 
                                        
                                                | 460 | schizolysigenous | 8,749 | ceghilnosuyz | 12 | 1,127 |